Generic Viagra | Erectile Dysfunction

Generic Viagra contains sildenafil citrate, which is a drug in the class of vasoactive agents called phosphodiesterase type 5 inhibitors (PDE5 inhibitors). The drugs in this pharmacological group promote relaxation of the smooth muscles in the penile bodies (corpora cavernosa and corpus spongiousum). This is achieved thanks to selective inhibition of PDE5 and the release of cyclic guanosine monophosphate (cGMP), which is a precursor of nitric oxide (NO). Both cGMP and NO are associated with improved blood flow, which means improved erectile function when it is restored in the genitals. Since the enzyme PDE5 is predominantly found in the penis, the effect of the drug is almost limited to the pelvic area.